

Glutathione Pen Kit
All-in-one Glutathione starter kit. Includes the Holte Pen®, 1,500mg Glutathione cartridges (2 x 750mg), case, micro needles, and a sharps bin. Everything you need to start using Glutathione at home, with close to 100% bioavailability.
Description
Everything you need to begin your L-Glutathione journey, in one complete kit.
Glutathione is widely regarded as the body’s most important antioxidant. Found in every cell, it plays a central role in detoxification, immune function, and protecting cells from oxidative damage. Unlike most antioxidants you consume, your body produces Glutathione naturally — but levels decline significantly with age, stress, toxins, and poor diet.
The Holte Glutathione Pen® delivers 750mg pharmaceutical-grade Glutathione per cartridge via subcutaneous injection, achieving close to 100% bioavailability. Oral Glutathione supplements are largely broken down in the gut before they can reach your cells — our pen bypasses this entirely.
Whether you’re looking to support detoxification, brighten your skin, strengthen your immune system, or protect against everyday oxidative stress, the Starter Kit is the simplest way to restore your Glutathione levels at home.
Kit includes:
- Holte Pen®
- Glutathione Cartridges (2 x 750mg)
- Travel Case
- Micro-needles
- Cold pack
- Sharps bin
- Wipes
For subscription orders you will only receive the Case and Pen on the first order.
Cellular protection, simplified.
Note: This product is intended for adult use only, designed to support a healthy lifestyle. It is not meant to diagnose, treat, cure, prevent, or manage any disease or medical condition. Always consult your healthcare professional.
What's Included
- Holte Pen™ — a sleek, reusable micro-needle device engineered for near-painless, high-absorption Glutathione delivery.
- Glutathione Cartridges (2 x 750mg) — pre-filled with 750mg pharmaceutical-grade Glutathione solution for maximum efficacy and purity.
- Fridge-safe storage/travel case — protects your cartridges and helps maintain optimal temperature between uses.
- Micro-needles — ultra-fine for comfortable, consistent application.
- Sharps disposal bin — ensures safe and responsible disposal of used needles.
- Pre-injection wipes
Dosage & Usage
Dosage & Protocol
Each pack contains two 750mg L-Glutathione cartridges. At the recommended 75mg (0.3ml) dose, you will receive 20 doses per pack, which provides approximately a one-month supply when following the standard protocol.
Recommended Routine
- The Loading Phase: Most individuals start with one dose daily for the first three days to rapidly elevate baseline levels.
- The Maintenance Phase: After the loading phase, transition to one dose every alternate day to keep your cellular antioxidant levels stable.
Tailoring Your Regimen
Glutathione requirements are highly individual. Depending on your personal goals and lifestyle:
- Some users prefer daily administration for intensive support.
- Others achieve excellent results utilizing the pen 1–2 times per week.
Listen to your body and adjust your frequency accordingly, or consult your healthcare practitioner to tailor the protocol to your exact needs.
How to Use Your Hōlte Glutathione Pen®
This guide provides step-by-step instructions to safely and effectively use your Hōlte Glutathione Pen® for subcutaneous injections.
Please follow the steps carefully to ensure proper use. Wash your hands thoroughly before you begin.
1. Setting Up the Pen
- Prepare the Pen and Cartridge. Remove the Holte Pen® and a Glutathione cartridge from their packaging.
- Allow the Glutathione cartridge to rest at room temperature for 5–10 minutes.
2. Unscrew the Cartridge Holder
- Take the lid off the pen to expose the clear cartridge holder.
- Unscrew the clear cartridge holder from the base of the pen.
- If the plunger is exposed, press it into the base of the pen with your finger.
3. Insert the Glutathione Cartridge
- Take the Glutathione cartridge and insert it into the clear cartridge holder with the silver tip going in first.
- Screw the clear cartridge holder (with the Glutathione cartridge inside) back onto the base of the pen firmly.
4. Prime the Pen
- Twist the base of the pen until the dose meter is fully extended.
- Push the dose meter back in and watch the plunger move up inside the cartridge holder.
- Repeat this process until the plunger touches the bung at the bottom of the cartridge and you feel resistance.
- Your pen is now prepped and ready for daily use. Continue with the steps below.
Administering your Glutathione subcutaneous injection
1. Attach the needle
- Take a 5mm needle tip from the pack and gently but firmly screw it onto the end of the Hōlte Pen®.
- Do not remove the needle tip cover yet.
2. Clean the injection site
- Use an alcohol wipe to clean the injection site.
- Choose a fatty area such as the abdomen (belly). Rotate the injection site each time to avoid skin damage or dimpling.
3. Set your dose
- Dosage: 75mg - 0.3ml per dose (20 doses per kit).
- Protocol: 1 x 0.3ml on alternate day. Listen to your body and adjust your frequency accordingly, or consult your healthcare practitioner.
- Twist the base of the pen until the pointer lines up with your prescribed dose.
- Remove both the outer and inner needle tip covers.
- The Glutathione solution has a strength of 750mg per 3ml cartridge (250mg/ml).
4. Administer the Injection
- Gently pinch the skin around the injection site, pulling it about 5mm away from the muscle.
- Place the needle at the injection site and press the pen down to pierce the skin.
- Press the button at the base of the pen to depress the plunger and administer the Glutathione.
- Hold the pen steady and count down three seconds before removing the needle.
5. Dispose of the Needle
- Carefully replace the outer needle tip cover.
- Unscrew the needle tip with the cover on and dispose of it in the sharps bin provided.
6. Store the Pen
- Replace the pen lid.
- Store the Holte Pen® in the fridge (between 2–8°C / 35.6–46.4°F) to keep the Glutathione cartridge fresh.
Important Notes for Safe Use
- Rotate injection sites to prevent skin damage or dimpling.
- It is normal to experience the following after an injection:
- A drop of Glutathione or blood on the skin.
- A small bruise if the needle wasn’t kept steady.
- A temporary red mark at the injection site. This will fade and is harmless. If concerned about visible marks, consider injecting in areas covered by clothing.
- Use a fresh needle for each use.
- Use Glutathione cartridges before their expiration date.
- Keep cartridges refrigerated.
Confirmation of understanding
By using the Hōlte Pen®, you confirm the following:
- You will administer Glutathione subcutaneously only, as instructed.
- You understand the risks (e.g., allergic reaction, infection) and commit to following the instructions exactly.
- You are competent to perform subcutaneous injections and will dispose of needles appropriately.
- Hōlte is not responsible for any adverse effects caused by improper use or failure to follow the instructions.
Important: This product is not intended to diagnose, treat, or cure any condition. Always consult a healthcare professional before starting Glutathione injections. Use sterile technique to avoid contamination or infection.
Storage & Shipping
Shipping
We ship all Glutathione products thermally protected, with DPD Next Day to keep them potent and effective. You must promptly refrigerate your Glutathione upon delivery.
- Orders placed after 10am are dispatched the next working day.
- Delivery arrives the day after dispatch.
- You’ll receive tracking details once your order is on its way.
- Shipping Monday - Thursday. Orders placed after 10am Thursday will be shipped the following Monday.
- Please ensure your availability to take delivery — any delays caused by failed delivery attempts are not the fault of Holte Health.
- Short periods out of cold storage do not affect the product, so place it in the fridge when you receive it.
Cost
Free UK shipping on orders over £100
£8 delivery for UK orders under £100
Returns
All sales are final. Due to the specific nature of our products, we are unable to accept returns or exchanges once an order has been processed and payment received.
Why do we have this policy?
- Temperature Integrity: Our Glutathione requires specific cold storage temperatures to maintain potency. Once a product leaves our facility, we cannot verify that it has been kept within the necessary temperature range. A returned product cannot be safely resold or reused without risking compromised quality. If temperatures go above 25 degrees we make delay sending until it cools.
- Strict Quality Control: We adhere to rigorous safety protocols during manufacturing and initial shipping. Accepting returns introduces a chain of custody break where we cannot guarantee the safety or sterility. For your safety and the safety of all our customers, we do not restock returned items.
Storage
Keep Glutathione in the refrigerator between 2 and 8°C.
Short periods at room temperature are fine during use, just return it to the fridge as soon as you can.
Do not freeze.
Keep out of reach of children and store in the original packaging.
Pairs well with

Glutathione Pen Kit
If you have any questions, you are always welcome to contact us. We’ll get back to you as soon as possible, within 24 hours on weekdays.
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Shipping Information
Free next-day DPD tracked shipping on all UK orders over £100. Orders placed after 10am ship the next working day.
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Customer Support
Have questions about Glutathione or your Starter Kit? Our team is here to help. Email us and we’ll respond within 24 hours on weekdays.
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FAQ's
Find answers to common questions about Glutathione, the pen device, dosage, and subscription management on our FAQ page.
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Contact Us
Reach out anytime. We’re happy to help with orders, product questions, or subscription changes.
The Science
Why Your Body Needs Glutathione
Glutathione is a tripeptide molecule found in every cell of your body. Often called the “master antioxidant,” it plays a central role in detoxification, immune defence, and protecting cells from oxidative damage. Unlike most antioxidants you consume, your body produces Glutathione naturally, but production declines significantly with age, chronic stress, toxin exposure, and poor diet. By your 40s, levels can drop by up to 50%. The Holte Pen® delivers pharmaceutical-grade Glutathione directly into your system with close to 100% bioavailability, bypassing the gut entirely.
Master Antioxidant
Glutathione is your body’s most powerful antioxidant, neutralising free radicals and reactive oxygen species that damage cells, proteins, and DNA. It also regenerates other antioxidants like Vitamin C and Vitamin E, amplifying your body’s total defence system.
Cellular Detox Engine
Your liver depends on Glutathione for Phase II detoxification the process of binding to toxins, heavy metals, and metabolic waste so they can be safely eliminated. Without adequate Glutathione, these harmful compounds accumulate and place your cells under increasing stress.
Immune & Skin Health
Glutathione is critical for the proper function of immune cells, particularly lymphocytes and natural killer cells. It also helps inhibit excess melanin production, supporting a brighter, more even skin tone from within one of the most sought-after benefits of consistent supplementation.
Protect your body at a cellular level
L-Glutathione is involved in virtually every cellular defence process, from neutralising free radicals to supporting liver detoxification and immune cell function.
Skin radiance
Glutathione helps inhibit excess melanin production and reduce oxidative damage to skin cells, supporting a brighter, more even complexion over time.
Deep detoxification
Essential for your liver’s Phase II detox pathways, Glutathione binds to toxins and heavy metals so your body can safely eliminate them.
Immune defence
Glutathione is critical for the proper function of lymphocytes and natural killer cells the front line of your immune system.
Oxidative protection
As the body’s master antioxidant, Glutathione neutralises reactive oxygen species that damage cells, proteins, and DNA; slowing the oxidative stress that accelerates ageing.
Your Glutathione Journey
Your body begins absorbing and utilising Glutathione immediately. Many users notice a subtle lift in energy and a general sense of feeling cleaner from within. Your cells are starting to clear accumulated oxidative damage.
Consistent use allows Glutathione to build in your system. Users commonly report improved skin clarity, a brighter complexion, and feeling more resilient fewer colds, faster recovery from illness or fatigue. Detoxification pathways are working more efficiently.
By now, the cumulative benefits are well established. Expect a noticeable improvement in skin tone and texture, stronger immune resilience, and a sustained sense of vitality. Your liver’s detox capacity is operating at a higher baseline.
Long-term supplementation supports sustained cellular protection against oxidative stress and environmental toxins. Users report maintained improvements in skin radiance, immune health, and overall wellbeing. Glutathione works cumulatively consistency is key to lasting results.
FAQs
Please read our FAQs page to find out more.
What is Glutathione and why do I need it?
Glutathione is a tripeptide molecule (made of three amino acids: cysteine, glycine, and glutamic acid) found in every cell of your body. It’s widely regarded as the body’s master antioxidant essential for detoxification, immune function, and protecting cells from oxidative damage. Your body produces it naturally, but levels decline significantly with age, stress, poor diet, and environmental toxins. Supplementing with the Holte Pen® helps restore those levels directly.
Why use a pen instead of oral Glutathione supplements?
Oral Glutathione is largely broken down by digestive enzymes in the gut before it can reach your cells studies suggest oral bioavailability can be as low as 3–5%. The Holte Pen® delivers Glutathione subcutaneously, bypassing the digestive system entirely and achieving close to 100% bioavailability. This means more of the active compound actually reaches your cells where it’s needed.
Does the injection hurt?
The Holte Pen® uses ultra-fine 4mm micro-needles designed for subcutaneous (just under the skin) injection. Most users describe the sensation as a brief, mild pinch — far less uncomfortable than a standard blood test or vaccine. Injecting into a fatty area like the abdomen and rotating your injection site each time helps minimise any discomfort.
How quickly will I notice results?
Individual experiences vary, but many users report noticing improvements in skin clarity and energy levels within the first 1–2 weeks. Deeper benefits such as improved immune resilience and detoxification support tend to build over 1–3 months of consistent use. Glutathione works cumulatively, so regular use delivers the best results.
Can I use Glutathione alongside the NAD+ Pen?
Yes. Glutathione and NAD+ complement each other well. NAD+ supports cellular energy production and repair, while Glutathione protects cells from oxidative damage and aids detoxification. Many of our customers use both as part of their daily wellness routine. We recommend injecting at separate sites and consulting your healthcare professional if you have any concerns.
How should I store my Glutathione cartridges?
Keep your Glutathione cartridges refrigerated between 2–8°C at all times. Short periods at room temperature during use are fine just return the pen to the fridge promptly after your injection. Do not freeze. We ship all orders with thermal protection and cold packs to maintain the cold chain during transit.
