Restore your NAD+ for
The most bioavailable NAD+ supplement in the UK.
- Pharmaceutical-grade NAD+
- 3rd Party Tested
- Vertically integrated production
Healthy ageing from within
We don’t just follow science, we lead with it. Holte is redefining wellness with precision formulas and a commitment to purity, performance, and purpose.
Made by us
Our NAD+ is produced under our oversight to strict GMP standards. No middlemen. Fairer pricing.
Pharmaceutical-grade NAD+
Developed to bypass digestion and deliver pure NAD+ directly to your cells where it’s needed most.
Science-Led Innovation
Built on world-class longevity research and peer-reviewed studies.
Tested. Retested. Verified.
Every supplement batch is third-party tested for purity and performance.
The Science
NAD+ declines up to 65% between ages 30 and 70
NAD+ is a coenzyme found in every living cell that fuels energy production and cellular repair. Research shows levels naturally fall with age, contributing to fatigue, slower recovery, and accelerated ageing.
Relative NAD+ levels (%)
Choose your NAD+ protocol
Made in our own lab and third-party tested for reassurance, giving you trusted wellness at the best value.
NAD+ Pen® Starter Kit (NAD Pen + 1000mg + Case + Micro Needles)
NAD+ Pen Refill Cartridge Kit (1000mg NAD+)
As we age, levels of NAD+ naturally decline, leading to a decrease in cellular health and efficiency. Supplementing with NAD plus can help restore metabolic balance, enhance energy production, and possibly reduce some effects of ageing.
— Dr David SinclairHarvard scientist pioneering research on longevity
In their words
Featured Stories
“Back to running at my best”
“Trust the science, remove the guesswork”
“Direct delivery system for healthy ageing”
Fuel your body at a cellular level
NAD+ supports over 500 enzymatic reactions in your body. Our pen delivers pharmaceutical-grade NAD+ — selected for purity, absorption, and real results.
Sustained energy
NAD+ fuels mitochondria — your cells' power plants — for all-day energy without stimulants.
Mental clarity
Supports brain cell repair and neurotransmitter function for sharper focus and cognition.
Recovery & repair
Activates sirtuins and PARP enzymes that repair damaged DNA — key to healthy ageing.
Better sleep
Regulates circadian rhythm and cellular processes linked to deeper, more restorative sleep.
FAQs
What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring molecule found in every cell of the body. It plays a crucial role in cellular energy production, DNA repair, and overall cellular health.
How does the Holte NAD+ Pen work?
Our wellness pen delivers a precise micro-dose under the skin, designed for smooth absorption and consistent results. It’s quick, discreet, and easy to use.
How-to-use guide can be found here.
Who is it designed for?
The pen is made for adults who want more energy, focus, and healthy ageing support. Whether you’re a busy professional, someone focused on beauty and skin health, or looking to recover faster from exercise, it’s a natural supplement addition to your wellness routine.
How often should I use it?
Many people begin with daily use, then naturally adjust to three or four times per week. Others choose to add extra sessions when they want an additional boost, for example after exercise or during particularly busy periods.
What makes this better than tablets or IV drips?
The pen is portable, more affordable than IV therapy, and offers stronger absorption compared to oral supplements. It’s designed for people who want results without inconvenience.
Can our products treat medical conditions?
No, the NAD+ Pen is not intended to diagnose, treat, cure, or prevent any disease or condition. Its purpose is to support and encourage a healthy lifestyle.
Are there any side effects?
Side effects are uncommon, but individual responses may vary. If you experience any unusual reactions, discontinue use and consult a healthcare professional.
Can it replace a healthy lifestyle?
No. The pen is most effective when combined with balanced nutrition, exercise, and good sleep habits. Think of it as a supplement enhancer, not a replacement.
When will my order arrive?
We ship all NAD+ products thermally protected, with DPD Next Day to keep them potent and effective. You must promptly refrigerate your NAD+ upon delivery.
- Orders placed after 10am are dispatched the next working day.
- Delivery arrives the day after dispatch.
- You’ll receive tracking details once your order is on its way.
- Shipping Monday - Thursday. Orders placed after 10am Thursday will be shipped the following Monday.
- Please ensure your availability to take delivery any delays caused by failed delivery attempts are not the fault of Holte Health.
How should I store my NAD+?
We ship all NAD+ products in insulated protected packaging with DPD Next Day to help maintain potency.
Please refrigerate your NAD+ as soon as it arrives. Short periods out of cold storage do not affect the product, so place it in the fridge when you receive it.