The Holte NAD+ Pen™ is designed to be reliable, easy to use, and stress-free. But like any device, first-time users may run into small challenges. The good news is that almost all issues have quick and simple solutions. This guide will walk you through the most common questions and fixes so you can stay confident in your routine without needing extra support.
Why Troubleshooting Matters
Our goal is to make sure you never feel stuck. By sharing answers to common questions, we reduce the time you spend searching for help and keep your NAD+ journey smooth. Whether your pen isn’t priming, a cartridge looks unusual, or you’re unsure about comfort, we’ve got you covered.
Common Issues and Fixes
1. The pen isn’t priming
What’s happening: Sometimes a new cartridge has a small air bubble, preventing the liquid from reaching the needle tip.
Solution:
- Turn the dosage dial slightly higher than your usual setting
- Press the plunger firmly until a small drop appears
- Reset the dial to your correct dose
This should solve the issue within seconds.
2. Cartridge leakage
What’s happening: A loose connection or over-tightened pen body can sometimes cause leakage.
Solution:
- Check that the cartridge is seated correctly
- Screw the pen body until snug, avoid over-tightening
- Wipe any residue and try again
If leakage persists, replace the needle and cartridge to rule out damage.
3. The injection feels uncomfortable
What’s happening: Mild discomfort can occur if the angle or site isn’t ideal.
Solution:
- Switch injection sites (abdomen, thigh, or back of the arm)
- Vary your angle (45° vs. 90°)
- Make sure the needle is fresh and sharp
Most users find injections almost painless once they find their preferred site.
4. Plunger feels stuck
What’s happening: This usually means the cartridge wasn’t fully primed, or there’s an air bubble.
Solution:
- Remove the cartridge and reinsert securely
- Prime the pen by pressing until liquid appears at the tip
- Try again at your normal dose
5. I see a small bruise at the site
What’s happening: Occasionally, a small blood vessel is touched during injection.
Solution:
- This is harmless and typically resolves in 1–2 days
- Apply light pressure immediately after removing the needle
- Switch to a different site next time
Pro Tips for Smooth Use
- Rotate injection sites: Prevents sensitivity or irritation
- Use a new needle every time: Ensures maximum comfort and safety
- Store correctly: Keep refrigerated when not in use. For a more comfortable experience, allow the pen to sit at room temperature for 10–20 minutes before injecting to reduce stinging.
- Stay consistent: A routine produces the best results.
When to Contact Support
While most issues are resolved with these quick fixes, you should contact Holte support if:
- You experience repeated cartridge leakage after trying a replacement
- The plunger does not move even after re-priming
- You notice unusual pain or swelling at injection sites
Our team is always available to assist, but in most cases, you won’t need us, this guide covers the common challenges.
Peace of Mind for First-Time Users
Remember, the Holte Pen was designed for first-time users. If you can follow a short checklist, you’ll find it intuitive. Over time, it becomes as simple as brushing your teeth, automatic, quick, and part of your lifestyle.
Final Thoughts
Don’t let small issues interrupt your routine. With this troubleshooting guide, you’re prepared to handle the most common challenges quickly and confidently. The Holte NAD+ Pen is safe, reliable, and built for real life, meaning you spend more time feeling energised and less time worrying about the process.
Need a fresh set of cartridges? Order Holte NAD+ refills today so your wellness routine never skips a beat.
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Best NAD+ Injection Pen: Why Holte Leads the Way